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PROTACs & Molecular Glues PROTACs® (PRoteolysis-TArgeting Chimeric molecules) artificially hijack the components of the UPS to degrade a target protein. PROTAC drugs are hetero-bifunctional small molecules that contain two functional ligands connected via a linker; one ligand binds to a target protein and the other ligand binds to an E3 ligase. Learn More E3 Ubiquitin Ligases […]